Which ionization technique is commonly used in mass spectrometry?

Electrospray ionization is a commonly used ionization technique in mass spectrometry. In this technique, a high voltage is applied to a liquid sample, typically containing analytes dissolved in a solvent. As the sample emerges from a fine capillary, the applied voltage causes the solvent to evaporate, leaving charged analyte molecules in the gas phase. These charged ions can then be manipulated and detected by the mass spectrometer. Electrospray ionization is particularly useful for analyzing biomolecules such as proteins, peptides, and nucleic acids.